A new, never heard of before study purports to have this COVID bug figured out. The abstract:
The receptor-binding domain (RBD) of the SARS-CoV-2 spike protein plays a crucial role in binding the human cell receptor ACE2 that is required for viral entry. Many studies have been conducted to target the structures of RBD–ACE2 binding and to design RBD-targeting vaccines and drugs. Nevertheless, mutations distal from the SARS-CoV-2 RBD also impact its transmissibility and antibody can target non-RBD regions, suggesting the incomplete role of the RBD region in the spike protein–ACE2 binding. Here, in order to elucidate distant binding mechanisms, we analyze complexes of ACE2 with the wild-type spike protein and with key mutants via large-scale all-atom explicit solvent molecular dynamics simulations. We find that though distributed approximately 10 nm away from the RBD, the SARS-CoV-2 polybasic cleavage sites enhance, via electrostatic interactions and hydration, the RBD–ACE2 binding affinity. A negatively charged tetrapeptide (GluGluLeuGlu) is then designed to neutralize the positively charged arginine on the polybasic cleavage sites. We find that the tetrapeptide GluGluLeuGlu binds to one of the three polybasic cleavage sites of the SARS-CoV-2 spike protein lessening by 34% the RBD–ACE2 binding strength. This significant binding energy reduction demonstrates the feasibility to neutralize RBD–ACE2 binding by targeting this specific polybasic cleavage site. Our work enhances understanding of the binding mechanism of SARS-CoV-2 to ACE2, which may aid the design of therapeutics for COVID-19 infection.
ACE2? ACE2? ACE2? Hmmm. Might??? Oh, yeah, it’s the same cellular structure I was writing about here on March 18th, at TPC on March 10th, at FP on March 9th, and back here on March 6th. I’m not a bio-medical pathologist, I just play one on the old blog – five months before the real guys come along. Get it here first, from the latter sources later, or from the MSM never (they say something about “a mask”).
As the dedicated professionals of the public disinformation and communist programming cabal reel from one sniffle-based hoax, they grapple with how to deceptively implement another.
John Marshall keeps a picture of Breonna Taylor in his office at the headquarters of Kentucky’s largest school district, a visual reminder, he says, of the need for curriculum changes that better honor and focus on Black stories.
Taylor, a Black emergency medical technician, spent her senior year of high school at Kentucky’s Jefferson County Public Schools, where Marshall, the district’s chief diversity officer, has been leading a system-wide revamp of teaching materials and practices.
Good golly! It’s another “education” story that has it all:
Chief diversity officer!
Shifting the focus of dumbing it down!
Minority majority in Kentucky (they ain’t alone, ‘Murica)!
Neo Tower of Bable confusions!
“Virtual” learning (which virtually isn’t)!
Equity and inclusion everywhere! (just like Holocaustianity, just maybe not quite as important?)
81% of publik skool teechaz supporting Boisterous Lying Marxists!
CONTROL!!!
New “perspectives!”
Lies!
More lies!
Hyphenationated paperwork-citizens!
Likely CIA front company psy-ops!
Those meaningful conversations no SJW or globopedo will tolerate! Hey, yeah. Let’s talk about Cannon Hinnant’s murder by that… Oh, okay, I’ll show myself out the door!
Saint Floyd of the Opioids!
And, much more!
You’ve probably identified the biggest issue with this crock of shit, right? Having succeeded so brilliantly in destroying the curriculum and turning off the young minds, these changes have nothing to take root in. What else, really, can they do that they’re not doing now? White guilt trip sessions? Daily beatings? Equity lynchings?
Who the hell cares? Not you. You homeschool! You’d damn well better.
Here’s another murder that won’t make any national headlines.
Police said Tuesday night that three teens, Keyshara Michelle Deans, 19, Nezyiha Zamir Collins, 19, and Tyreek Qumay Rodgers, 18, were all arrested and charged with accessory after the fact to murder.
Authorities were still looking for 17-year-old Devin Cordell Jones. A juvenile petition and secure custody order for the murder of Veronica Lee Baker were being sought for Jones. On Wednesday morning, the teen was taken into custody and charged with Baker’s murder.
Yes, the names are giveaways. And, yes, some online commenters have picked up on several other suggestions and too-common anomalies. I always, as you know, like to look at the school profile. Here’s Garner High, from which the victim had just graduated. Rest assured that the suggestions, anomalies, and modern cultural problems were there and played their respective roles. It can perhaps be summed up best in the graph one finds upon clicking the “Students” button. My intuition was rewarded; that’s quite the change from thirty years ago – and it’s a pattern that’s repeating across NC and everywhere else. Demographics = destiny. Destiny increasingly looks like homicide.
These are not schools. They’re not even close anymore. Now, they’re starting to resemble hunting grounds.
Well, this story is in keeping with the earlier post about my new book. And, like the sad Mass schools article from the other day, it has many, if not all, of the interesting components.
As the pandemic has ravaged the United States, some Americans are finding that a second citizenship or permanent residency has a renewed appeal. “Even the most basic things have become politicized,” said Anjelica Triola, 34, a director of marketing at Wethos, a company that helps freelancers grow their businesses, who also has Italian heritage.
She brought up protective masks as an example. “My father’s parents came here to be free, and there is an entire generation that are trying to go back now to pursue similar freedoms,” she said.
Paperwork Americans;
First and second generations migrants that never assimilated;
Dual (paper) loyalties;
Single mothers;
Admission that the “Land of the Free” no longer is;
Boomers(!); and more!
We ran here for the good times and helped wreck this nation. Now that the fun is over and the fires are burning, it’s time to go (back to the real) home! And, these paperwork jobs are or were marginal Americans, not quite Anglo, but close enough, right? They’re far from the worst dual-nationals too. Here’s hoping that they find peace and nationalism in their true nations. Americans used to enjoy something like that, you know, here in America. Crazy, yes.
Get Out! kids, if you’re thinking about moving, remember the criticalities of compatibility. If you go, go to stay and stay to integrate. You’ll never be [fill in the blank nationality] unless it’s already literally in your blood. But your grandkids might. I keep writing “kids, kids, kids” for a reason! No Boomers, please. Gen X, we’re on the line and I’m leaning towards a “no.”
The book is proving about as popular as I feared it would, though I hope the few of you who have downloaded it find it helpful.
Lately, one of my selected nations has been in the news for all the wrong reasons.
Belarus is towards the end, written about when I was running out of steam and received the barest mention:
A little larger and inland, landlocked. Ethnically Belarusian and other Euros. 80% Eastern Orthodox, with more Roman Catholic, Greek Catholic, and various Protestants. An IQ like Lithuanian. Flat and cool. A developed economy where privatization is still in progress. They’re not on the Euro, using the “new” Ruble – theirs, not the Russians. They speak Russian and Belarusian, officially.
And now, oh, no! They have – surprise, surprise – political problems. What country doesn’t?
Here’s how I see the situation with Lukashenko, Putin, and the protesters: for [reasons], what’s happening there is still better than what is happening at the same time in dying Amerika. Watch Belarus. Whatever comes of the current turmoil will still be more pleasant than what unfolds in the US.
I wrote another column on the gamboling fun of organized sports entertainment in 2020. In short: it’s not happening, or not happening much, sorry. Be your own sport. Buck the trends and get in shape. There. I may have more on that later. For now, consider the following, which I deemed of greater value:
Perplexed as always, the Disciples asked Jesus to explain what caused their failure in doing that which He did with ease. “He answered, ‘Because you have so little faith. In truth I tell you, if your faith is the size of a mustard seed you will say to this mountain, “Move from here to there,” and it will move; nothing will be impossible for you.‘” Matthew 17:20.
We, all of us, could use a little more faith these days.
One thing leads to another. I was reading a Mary Cuff article at Crisis the other day and, in a very rare move, I clicked on a pop-up ad. And I’m glad I did because it led me to a video presentation by Church Militant featuring Father Paul Kalchik.
Kalchik is almost a household name in right-wing, traditional, American Catholic households. We, some of us, have followed his titanic battle against the forces of the sodomitical wolves currently at work against both the Church and the Flock. Because of HOAXID-19, it was, of course, a virtual teleconference. Because of his amazing victory, and subsequent lavender mafia retaliation, Kalchik joined the show from a place of hiding. However, there is no hiding the magnitude of his inspirational message.
Part of the missive, which amounts to an hour-long homily of peace, was the above-cited parable about the mustard seed of faith. My thoughts of late, regarding the state of the world and especially the terminal decline of the American nation and the United States, have led me to consider that our main problem is the woeful character of the people. I summed it up to myself as people being both wicked and stupid. One is bad enough on its own; together they are a dreadful combination as one amplifies the other. We see the results all around us: a people, barely surviving, who almost gleefully play the fool’s part in accepting hoaxes, lies, degradations, and disaster, all wrought by the same usual suspects who have lied to, robbed, and murdered humanity for centuries.
Father Kalchik sees all of this too. He takes a calmer, more reflective approach to it than some (not looking at your author, no…). He names the problem and those behind it. Call them globalists, globopedos, the illuminati, fear-mongers, or whatever you will, they are only the dark one and his loathsome servants. It really is that simple. And, Father K. offers a surprisingly simple solution for us: Faith and Prayer. Well, those simplicities along with a healthy dose of RESISTANCE, which is the title of CM’s conference.
He gives concrete steps anyone can take to fight the forces of hell. It’s all bound by faith in Jesus Christ. It takes strength through prayer. And it moves through calm questioning, learning, and action.
Due to his own circumstances, he’s understandably taken with the technology of encryption. I do wonder about his suggested “digital catacombs.” Have we come that far, or retreated that far? Perhaps. You be the judge once you’ve seen or heard the message in full.
Along the way, in the presentation, Father tells some of his own backstories. He adds a great quote from the late Archbishop Fulton Sheen about not going with the flow: “dead bodies float downstream.” He also discounts just a select few of the more recent hoaxes set into motion by the luciferians, including:
The general uselessness of the tacky popular culture;
Y2K (I’d forgotten about that!);
Global Warming;
Climate Change;
White Guilt;
LGBT+P; and
Corona hype and hysteria.
Again, he only chose a few and only those from the more recent decades of memory. In every case, all cases, it is the same evil at work.
His ultimate point is that, eternally, evil cannot win. Without our consent and participation, it really can do little more than annoy us who are in the world but not of it. Still, a certain Carpenter told us to take care of business until He returns. We have a solemn obligation to resist. That’s where so many of us – at times, all of us – fail. Fortunately, inspirationally, the fix is as small as the mustard seed. It’s high time to move some mountains.
Please take an hour out of your busy, locked-down, masked lives and watch the following (or, as I did, listen to it while doing something else):
Fr. Kalchik, CM, June 2020.
Furthermore, kindly pray for Fr. Kalchik. For a brief explanation of why he’s “on the run,” please read THIS and THIS. In summary, he took a page from the Lord and Saint Paul and mortally angered the sodomite usurpers by burning one of their sacrilegious artifacts. In a (perhaps distantly) forthcoming novel, I have a heroic character based on Kalchik. In a literal world that frequently out-shocks the most dystopian fiction, it’s good that we have real characters, real heroes, like him.
Now, all, please acquire the seeds, and move those mountains.
In a dark season of pestilence, COVID has reduced to tatters the illusion of American exceptionalism. At the height of the crisis, with more than 2,000 dying each day, Americans found themselves members of a failed state, ruled by a dysfunctional and incompetent government largely responsible for death rates that added a tragic coda to America’s claim to supremacy in the world.
The author goes on and into details about other failed states and empires. He might be correct about all of that, but, as we have been so reliably informed so many times, Amerika really is different. Just check the Founding poem on our big girl statue! (Hey, I wonder how many communists Lady L will crush when they finally pull her down??????)
Amerika is, and always has been, just an idea, a simple, incoherent, misleading creed. If there’s any minor problem with it at present, then all we have to do is get out an eraser and change a few words or something. Nations, after all, are just words and vague ideas, and not borders, blood, and people.
Pandemics are like economic issues: all they require are more immigrants, who were really always the best Amerikans anyway.
Just when one thinks the satanists who operate the country’s failed public “schools” can’t sink any lower, they do. A new trend in “education” has teachers calling the cops and CPS on parents whose children don’t tow the moronic line on Zoom faux classes. Pot, kettle; black as educrat hearts.
If there’s one thing the public school system shouldn’t be doing right now, it’s making life even more hellishly difficult for parents. And yet many teachers in the state of Massachusetts are contacting the authorities to report parents for suspected child abuse when kids fail to show up for Zoom classes.
“Massachusetts school officials have reported dozens of families to state social workers for possible neglect charges because of issues related to their children’s participation in remote learning classes during the pandemic shutdown in the spring,” The Boston Globe reported on Saturday.
This story really has it all:
The little girl in the picture is wearing a fear hoax mask, while at home, putatively during a remote “class.” W.T.H?
Immigrants who can’t speak English.
Working mothers.
Single mothers.
Mass dysgenic effects.
Textbook SJW behavior: lies, doubling down, and projection.
Evil (and, I really mean that word) officials, who themselves abuse children, daring to accuse parents of the same thing by not playing the fool’s game of double-fake schooling.
Children, temporarily freed from direct attacks, still learning nothing.
A school district with elementary schools cursed with shifting demographics and collapsing academic performance. (Those usual go hand in hand).
Police state intimidation tactics.
Bullying and abuse (by a school) of a mentally challenged child and his family.
Lazy, wicked power-tripping, writ large.
Pundits who think the schools should be doing anything but closing and bulldozing.
Get your children out of these luciferian communism centers. Get them completely out, to include out of all contact, even the virtual. Homeschool or face terminal failure and accusations that you committed the crimes of the system.
Forget Kamala (Javier Bardem?). Jo Jorgensen is the lead on the LP ticket – not that she or Mr. Cohen has a snowball’s chance. But, gurl, she’s come a long way. Tomorrow is the anniversary of the BIG 19(!), which should have never passed and should have been repealed when doing so still mattered. It doesn’t, nor does the LP.
Still, it’s nice that Jorgensen wants to end big government. Such sentiment would have come in handier (if acted on) 50 or 100 years ago. Not that the LP would have been good for anything then if they had held their current principles. They’re the party of principle, they say. Some of the stated ones, hers and theirs, are pretty good guides for pretty good people. Some of them.
Those principles also include no stance on murdering babies, but full support for open borders and for free trade. And, as always, for MJ and dope. In other words: Libertardian = luciferian globalism for upper-middle-class potheads.
It’s ironic that they operate as if everyone neatly fit into a homogenous nationalist framework, while they actively discount the need for the same.
Again, not that any of this matters, for 2020 or from here out. This, I think, concludes my LP remarks both for this election and for the hereafter. Too little, too late, and too weak.
The world lost a legend last week. Bobby Banks, a heroic educator, and barber in Augusta, GA, died at the age of 87. I’m a little down about this and not sure how to begin, so I’ll just freestyle it.
Mr. Banks was formerly my barber, the greatest I’ve ever known, and a very good friend. He started cutting hair in another age while in the US Navy. He taught my parents in high school. Rather, he taught my Mother and tolerated Daddy. He was the principal at both my junior high and high schools, back when both were concerned with education. As luck wouldn’t have it, he skated ahead of me by a year or two. I never had the privilege of getting in trouble with him.
We had long talks about education. I know much about his time in the schools and his retirement. We spoke frankly about the changes over the years. He was the kind of man the public schools desperately need today (or needed 25 years ago) but which they simply will not have anymore. He was happier as a barber anyway.
He was fantastic with the blades – one of several business ventures he maintained. He was the real deal: providing manly cuts with razor-close precision, unafraid to perform a little impromptu surgery the way they did 200 years ago – usually without consulting the patient first. “Did that sting?”
I know tons of people who loved him in his academic role. The stories about his demanding, caring, off-beat, and semi-scofflaw ways are legion and legend.
“Where do you think y’all are going?”
“To Burger King, Mr. Banks. We can’t stand school today.”
‘Me either. Let’s go.”
He bent rules to do the right thing.
“You boys will be sorry you broke those windows.”
“We are sorry, Mr.—“
“The cops are coming! Shut up and get in my trunk!”
He was too good, especially for what’s become of the local ed scene. Back then, things, scores included, looked up, not down.
I got to know him in ways many students did not. He cut my hair before my wedding. He’d humor my daughter’s instructions and then cut my hair the way he always did. When Daddy was sick and dying and couldn’t leave the house, Mr. Banks made a house call – I know of no other barber who does or did. The connection was multi-generational. He proudly told me that his father and my grandfather used to raise and fight gamecocks together (back when America was a free country). He’s the only person I’ve ever lent my vintage cockfighting manuals to, the only one who was interested. The only one who, or one of few, who knew what Grit ‘n Steel was. He’s the only other man I ever knew who had one of Ethan Allen’s rare Bicentennial wall rugs – his copy hung in the shop at Daniel Village.
They don’t make them like they used to and I’m not sure they ever made another like him. All good things and people come to an end, even the very best. My condolences to his wife, family, friends, co-workers, and community left pooer by his passing, though richer for the knowing.
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