M-m-m-my CORONA! Deconstructing a Viral Construct (or Two)
I may have been remiss not to mention the Novel Coronavirus 2019 on these digital pages before. As Pop Smoke would have said, “My bad!” A song to get us in the mood for a pandemic!
When you gonna sicken me, s-sicken me?
Is it just a matter of time, CORONA?
Is it q-q-quarantine, q-quarantine?
Or is it just a hack in my throat, CORONA?
*Deepest, deepest, low-grade fever apologies to Doug Fieger, Berton Averre, and The Knack.
Over at Freedom Prepper – which is slowly rebounding(!) – I have been covering the vicious little bug for a few weeks now. Check that out – pretty much any recent link or blurb. There’s a lot to this epidemic and a lot we are not being told. Let’s get this out of the way: I think it’s either about to blow over or about to blow up. Some tips, in case it’s the latter. And, if you trust “your” government, that in China, the mainstream media, the WHO, etc., then please keep track of the “official” damage. The last time I checked the math, on Friday, February 21st, 2,233 of the related (reported) deaths, out of 2,250 total, were in China. That’s 99.244%. The vast majority of cases and of recoveries are also in Asia, most being within mainland China.
Let’s get this out of the way, too: while it appears the nCoV19 can infect nearly anyone (it’s a cold virus strain, BTW), it also appears to be much more dangerous to Asians. And, from what I’m hearing, it really savages the Asian male population. But, don’t take my word for it:
In 2019, a new coronavirus (2019-nCoV) infecting Humans has emerged in Wuhan, China. Its genome has been sequenced and the genomic information promptly released. Despite a high similarity with the genome sequence of SARS-CoV and SARS-like CoVs, we identified a peculiar furin-like cleavage site in the Spike protein of the 2019-nCoV, lacking in the other SARS-like CoVs. In this article, we discuss the possible functional consequences of this cleavage site in the viral cycle, pathogenicity and its potential implication in the development of antivirals.